Table 2 The top 20 response DMCs list with p value < 1e−4. The response DMCs were sorted by the p value. CpG chromosome and position, regression p value, beta value (coefficient) and the annotated closest gene information (including genomic Annotation, Distance to TSS, Gene Name, Gene Type, and Gene Description of the closest gene) were provided
chr.position | p value | Beta | Annotation | Distance to TSS | Gene Name | Gene type | Gene description |
|---|---|---|---|---|---|---|---|
chr18.48723610 | 3.49E−08 | − 0.22733 | exon (NM_016626, exon 1 of 2) | 440 | MEX3C | Protein-coding | mex-3 RNA binding family member C |
chr1.150532375 | 7.49E−07 | − 0.39527 | TTS (NR_104133) | 7971 | MIR4257 | ncRNA | microRNA 4257 |
chr10.105647890 | 1.17E−06 | 0.893509 | intron (NM_024928, intron 9 of 9) | 30,051 | STN1 | Protein-coding | STN1 subunit of CST complex |
chr11.10679586 | 1.56E−06 | − 0.58556 | intron (NM_001206880, intron 1 of 19) | − 5739 | MRVI1 | Protein-coding | Murine retrovirus integration site 1 homolog |
chr3.156848563 | 1.97E−06 | − 0.14999 | Intergenic | − 7773 | LINC00880 | ncRNA | Long intergenic non-protein-coding RNA 880 |
chr12.129252225 | 2.68E−06 | − 1.11703 | Intergenic | 56,277 | SLC15A4 | Protein-coding | Solute carrier family 15 member 4 |
chr1.50834156 | 3.76E−06 | 0.153745 | Intergenic | 54,958 | DMRTA2 | Protein-coding | DMRT-like family A2 |
chr16.56553641 | 3.90E−06 | − 0.13719 | intron (NM_031885, intron 1 of 16) | 294 | BBS2 | Protein-coding | Bardet-Biedl syndrome 2 |
chr6.99283220 | 3.95E−06 | − 0.12451 | exon (NM_005604, exon 1 of 1) | 771 | POU3F2 | Protein-coding | POU class 3 homeobox 2 |
chr22.46519089 | 4.61E−06 | − 1.1146 | Intergenic | 9524 | MIRLET7B | ncRNA | microRNA let-7b |
chr1.25228801 | 4.78E−06 | − 0.30407 | exon (NM_004350, exon 5 of 5) | 17,105 | MIR6731 | ncRNA | microRNA 6731 |
chr2.241976241 | 4.88E−06 | − 0.48453 | exon (NM_001080437, exon 5 of 32) | 38,207 | SNED1 | Protein-coding | Sushi, nidogen and EGF-like domains 1 |
chr7.139187227 | 5.05E−06 | − 0.39751 | Intergenic | − 18,809 | KLRG2 | Protein-coding | Killer cell lectin-like receptor G2 |
chr4.79545349 | 5.32E−06 | 0.366908 | Intergenic | − 21,798 | LINC01094 | ncRNA | Long intergenic non-protein-coding RNA 1094 |
chr16.66554996 | 5.35E−06 | 0.684785 | intron (NR_073520, intron 5 of 8) | 29,028 | TK2 | Protein-coding | Thymidine kinase 2 |
chr11.68608981 | 5.63E−06 | − 0.13725 | intron (NM_001876, intron 1 of 18) | 402 | CPT1A | Protein-coding | Carnitine palmitoyltransferase 1A |
chr4.122871430 | 5.71E−06 | 0.274039 | intron (NM_001366479, intron 1 of 10) | 1784 | TRPC3 | Protein-coding | Transient receptor potential cation channel subfamily C member 3 |
chr11.8364991 | 6.74E−06 | 0.562738 | Intergenic | − 74,658 | LMO1 | Protein-coding | LIM domain only 1 |
chr9.117026652 | 6.75E−06 | 1.475667 | exon (NM_032888, exon 29 of 61) | 54,939 | MIR455 | ncRNA | microRNA 455 |
chr3.183873096 | 6.93E−06 | 0.345301 | promoter-TSS (NM_004423) | − 68 | DVL3 | Protein-coding | Disheveled segment polarity protein 3 |