Fig. 3

Genome feature and functional enrichment analysis of the response DMCs. A Genomic features and blood regulatory element enrichment analysis of the response DMCs with p value < 1e−3 and p value < 1e−4. Fisher test: *: p value < 0.01. B–D Functional enrichment analysis of the response DMCs. Enrichment of functional grouping of genes through the biological process, groups of the genes in the same pathway through KEGG, pathway interaction database as well as the WikiPathways, and the similar domain and features of the gene’s product proteins through PFAM and Interpro domain database were illustrated in (B), (C) and (D), respectively. The number of genes in each item and p value of the enrichment analysis was shown in the legend