Characterising sex differences of autosomal DNA methylation in whole blood using the Illumina EPIC array

Clinical Epigenetics

Table 2 Overlap of autosomal sex-associated differentially methylated positions reported in this study with previous literature in various tissues

Study	Tissue of interest	Sample size (number of individual samples in study)	Platform used for DNA methylation assessment	Number of autosomal probes identified	Percentage of saDMPs replicated (%)	References
Yousefi et al. (2014)	Cord blood	111 newborns	Illumina 450 k	3031	54	[21]
Mccarthy et al. (2014)	Meta analysis of 76 studies	6795	Illumina 27 k	184	0.54	[70]
Inoshita et al. (2015)	Peripheral leukocytes	117 adults	Illumina 450 k	292	15	[24]
Maschietto et al. (2015)	Cord blood	71 newborns	Illumina 450 k	2332	36	[69]
Xu et al. (2014)	Post-mortem prefrontal cortex	46 adults	Illumina 450 k	614	35	[66]
Hall et al. (2014)	Pancreas	87 adults	Illumina 450 k	470	18	[19]
Xia et al. (2021)	Post-mortem brain samples	1408 adults	Illumina 450 k	15,417	31	[7]
Inkster et al. (2021)	Placenta	293 adults	Illumina 450 k	162	73	[27]

ISSN: 1868-7083