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Fig. 10 | Clinical Epigenetics

Fig. 10

From: Batch-effect detection, correction and characterisation in Illumina HumanMethylation450 and MethylationEPIC BeadChip array data

Fig. 10

The influence of probe melting temperatures on batch-effect. For each of the five studies and two probe types (I and II), the relationship between probe oligonucleotide melting temperature (Tm) and batch correction (mean β shift) was examined. A subset of Type II probes in the EpiSCOPE and NOVI study data were observed to require more batch correction when the probe Tm is low

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