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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Predicting male fertility from the sperm methylome: application to 120 bulls with hundreds of artificial insemination records

Fig. 3

Genomic location and methylation status of fertility-related differentially methylated CpGs. Black and red dots represent DMCs that are hypo- and hypermethylated in subfertile bulls, respectively. The left y-axis indicates a log function of the methylKit q-value that reflects the significance of the DMC. Chromosomes are displayed on the x-axis. The grey line shows the density of CpGs10 analyzed by RRBS (number of CpGs10 analyzed per window, each window corresponding to the length of the chromosome divided by 300; right y-axis). While DMCs hypermethylated in subfertile bulls are scattered throughout the regions targeted by RRBS, hypomethylated DMCs concentrate at discrete and specific regions of the genome

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