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Fig. 5 | Clinical Epigenetics

Fig. 5

From: Epigenome-wide association study of bronchopulmonary dysplasia in preterm infants: results from the discovery-BPD program

Fig. 5

Biological functions and pathways predicted by epigenome changes in bronchopulmonary (BPD) cord blood. Pathway analyses done by Ingenuity Pathway analysis (IPA), ToppGene Suite, David Functional Annotation, and Reactome Pathway Database determined enriched biological functions and signal transduction pathways for the annotated 386 genes to 275 CpG loci associated with BPD risk. CXCR4 C-X-C motif chemokine receptor 4, HOX homeobox, NRBC nucleated red blood cell, PIP3 phosphoinositide 3, RAR retinoic acid receptor, RXR retinoid X receptor, RUNX1 runt-related transcription factor 1, VDR vitamin D receptor, VEGF vascular endothelial growth factor, WBC white blood cell

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