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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Epigenome-wide association study of bronchopulmonary dysplasia in preterm infants: results from the discovery-BPD program

Fig. 2

DNA methylation-based prediction of cord blood cell-type composition. A Box and whisker plot shows percent distribution of 7 blood cell types in preterm infants with or without bronchopulmonary dysplasia (BPD). Mean indicated by open dot within box, median, 25th and 75th percentile presented. B Variation in percent cell-type distribution by birth weight quintile and comparison with that in full-term infants. C Density plot of genome-wide methylation distribution comparing profiles of the 10 highest (brown) and 10 lowest (blue) nucleated red blood cell (NRBC) samples. Yellow box highlights demethylation in high NRBC samples. D Correlation of estimated percent NRBC with birth weight in preterm infants. E Correlation of aryl-hydrocarbon receptor repressor (AHRR) smoking biomarker (cg05575921) with estimated NRBC and distribution among BPD groups. CD4T CD4+ T cells, CD8T CD8+T cells, NK natural killer cells, Mono monocyte, Gran granulocyte

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Clinical Epigenetics

ISSN: 1868-7083

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