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Fig. 5 | Clinical Epigenetics

Fig. 5

From: DNA methylation regulates TIGIT expression within the melanoma microenvironment, is prognostic for overall survival, and predicts progression-free survival in patients treated with anti-PD-1 immunotherapy

Fig. 5

Flow cytometry analysis of TIGIT expression of pharmacologically demethylated melanoma cells. Representative SSC/FSC and FSC/TIGIT-PerCP/Cyanine5.5 dot plots of untreated and unstained (a), untreated (b), and 5‐aza‐dC treated A375 melanoma cells (c). d Flow cytometric histograms showing TIGIT expression of pharmacologically demethylated (5‐aza‐dC treated) compared to untreated A375 melanoma cell line

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