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Table 2 Differences in distributions of DNA methylation between neonatal necrotizing enterocolitis and normal control samples within defined genomic region classes

From: Selective hypermethylation is evident in small intestine samples from infants with necrotizing enterocolitis

Region

Diff.med (%)a

Diff.med (%)b

p value (W.holm)c

A: All Sites

0.60

1.31

0

B: Prom No CGI

0.46

1.58

0

C: Prom & CGI

0.01

0.08

1.19ā€‰Ć—ā€‰10āˆ’253

D: Intron/Exon No CGI

1.40

1.74

0

E: Intergenic CGI

0.14

0.25

0

F: Intron/Exon & CGI

0.06

0.19

0

G: CGI Shores

0.79

1.27

0

H: Intergenic

1.37

1.66

0

  1. CGI: CpG island
  2. aMedian difference between NEC ileum and non-NEC ileum
  3. bMean difference
  4. cAdjusted for multiple comparisons using Holmā€™s method