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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Ethical implications of epigenetics in the era of personalized medicine

Fig. 1

Epigenetic-based biomarkers to monitor human diseases. The effects of lifestyle, environmental exposures (at individual or transgenerational level) or the genetic background, among others, are well-known influencing factors of the epigenome. In spite of the growing number of proposed biomarkers associated with human diseases, some technical limitations need to be solved including the assessment of causality, the establishment of reference epigenomes or the cell-type specificity. On the ethical, political and social dimension a deep discussion on the role of epigenetics as determinants of health and the impact of public health policies and personalized medicine is required

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