Skip to main content

Table 1 Descriptive characteristics of the study groups. Average value and standard deviation are indicated

From: Transcriptional, epigenetic and metabolic signatures in cardiometabolic syndrome defined by extreme phenotypes

 

Blood donors (n = 202)

Controls (n = 20)

Lipodystrophy (n = 10)

Obese (n = 11)

Post-surgery (n = 10)

Adiponectin (µg/ml)

10.1 ± 6.3

10.7 ± 3.7

3.2 ± 2.3

5.9 ± 1.9

6.4 ± 2.6

AGE(years)

57.3 ± 11.1

40.7 ± 11

45.1 ± 9.6

46.3 ± 12.3

43 ± 12.6

ALT (U/L)

34.6 ± 12

27.1 ± 7.5

56 ± 12.7

35.7 ± 9.4

36.1 ± 17

AST (U/L)

25.5 ± 11.1

21.8 ± 6.9

39 ± 16.8

22.6 ± 3.8

18.9 ± 6.9

AT-IR

2.6 ± 2.5

1.9 ± 2.5

8.4 ± 7

7.2 ± 11.2

4.8 ± 5.4

BMI (kg/m2)

26.4 ± 4.9

 < 25

 < 25

45 ± 5.1

–

BW (kg)

76 ± 14.9

–

73.2 ± 9.7

137.9 ± 35.2

–

FFA (µmol/L)

189.3 ± 132.8

156.5 ± 103.3

259.6 ± 174.9

293.1 ± 164.6

232.2 ± 141.5

GLC (mmol/L)

5.4 ± 1.8

4.9 ± 1

8.3 ± 3.4

5.3 ± 0.6

5.3 ± 1.5

HDL-C (mmol/L)

1.6 ± 0.5

1.7 ± 0.4

0.8 ± 0.6

1.3 ± 0.2

1.3 ± 0.2

HOMA-IR

4.3 ± 4.9

2.5 ± 2.2

13 ± 10.5

7.1 ± 11.3

8.6 ± 18.4

hsCRP (mg/L)

1.9 ± 1.8

2.2 ± 1.2

2.3 ± 3.3

7.4 ± 6.9

2.9 ± 5.6

Insulin (pmol/L)

118.4 ± 117.1

76.4 ± 55.6

261.7 ± 262.3

190.6 ± 276.2

178.7 ± 294.3

LAR

1.8 ± 2.1

2 ± 2.1

2.3 ± 1.9

13.7 ± 6.6

5.5 ± 4.5

LDL-C (mmol/L)

2.9 ± 0.9

2.7 ± 0.8

1.7 ± 0.5

2.4 ± 0.8

2.6 ± 1

Leptin (ng/ml)

14.2 ± 14.7

19.8 ± 17.1

7.6 ± 7.8

74.1 ± 30.4

29.9 ± 21

TC (mmol/L)

5.3 ± 1.1

4.9 ± 1

4.2 ± 1

4.5 ± 0.8

4.1 ± 1.4

TG (mmol/L)

1.6 ± 0.9

1.2 ± 0.9

5.6 ± 5.5

1.9 ± 0.7

1 ± 0.4