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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Bisulfite profiling of the MGMT promoter and comparison with routine testing in glioblastoma diagnostics

Fig. 3

A Grouping of CpGs in MGMTe1 (CpG + 6 to CpG + 17) and MGMTi1 (CpG + 18 to CpG + 32) into methylation domains; CpG sites covered by MSP primers are indicated by arrows, CpGs analyzed with pyrosequencing (PyroMark) are indicated as a box at the bottom. B Correlation plots of absolute methylation data obtained by local deep bisulfite sequencing (MiSeq) and pyrosequencing (PyroMark) for CpGs + 10, + 11, + 12 and + 13; each dot represents the methylation level of the indicated CpG from a single sample; Pearson correlation coefficient is indicated together with trend line, confidence intervals and IDs of consistent outlier samples

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