Fig. 2
From: Novel epigenetic network biomarkers for early detection of esophageal cancer
FEM-modules derived from TCGA EAC cohort. Barplot lists the significant FEM-modules labeled by the seed-gene with the number of genes in each module given in brackets. Length of bars indicate the number of genes within the module that are significantly differentially methylated (DM), significantly differentially expressed (DR), jointly differentially methylated and differentially expressed (DM & DR) and the subset of these that exhibit anticorrelation between promoter DNAm and gene-expression. We display 3 modules defined by seed-genes, CTNND2, CCL20 and NCAM1. The node color indicates differential DNAm, with the border color indicating differential expression, as specified in the color-bars