Fig. 3

Receiver operating characteristic (ROC) curves of the urinary methylation markers FAM19A4, GHSR, MAL, miR-129, miR-935, PHACTR3, PRDM14, SST and ZIC1. For each marker, the ROC curves for urine pellet in the present study (black line) and for full void urine in the previous exploratory study (grey line) are visualized. The sensitivity is shown at the Y-axis, for 1-specificity at the X-axis. The area under the curve (AUC) of the present study is provided in the lower right corner, with the AUC of the previous exploratory study between parentheses [9]