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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Immune profiles and DNA methylation alterations related with non-muscle-invasive bladder cancer outcomes

Fig. 4

Genomic context enrichment analysis of CpG sites whose methylation state is significantly associated with recurrence-free survival. Enrichment analysis of (A) relation to CpG island and (B) genomic context of NMIBC recurrence-free survival associated CpGs. The 2528 CpGs from EWAS (P < 0.005) were tested for enrichment versus all modeled CpGs. The bar represents the 95% confidence interval. Mantel–Haenszel was used to test RFS-associated CpGs enrichment of CpG island-related gnome context. An odds ratio larger than 1 means enrichment, and an odds ratio smaller than 1 indicates depletion

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