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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Integrated 5-hydroxymethylcytosine and fragmentation signatures as enhanced biomarkers in lung cancer

Fig. 1

Overview of analysis pipeline and sample information. A The workflow chart of the study design. A total of 346 subjects, including 189 healthy volunteers and 157 lung cancer patients, were enrolled in analysis. 5hmC signals and fragmentation profiles were investigated in cfDNA 5hmC dataset. An integration model was finally constructed by combining cfDNA 5hmC features and fragmentation profiles for lung cancer diagnosis. B Representative images of hematoxylin and eosin (HE) staining in different histological types of lung cancers. Scale bar, 200 μm

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