|
Type
|
Target
|
Drug
|
References
|
|---|
|
HDACi
|
HDAC1
|
Quisinostat
|
[23]
|
|
SIRT1
|
Selisistat, Nicotinamide
|
[25, 28]
|
|
HDMi
|
KDM1A/LSD1/AOF2
|
GSK2879552, Bizine
|
[30, 33]
|
|
KDM2A/FBXL11
|
Daminozide
|
[32]
|
|
KDM5A/JARID1A
|
JIB-04
|
[35]
|
|
KDM5B/JARID1B
|
PBIT
|
[26]
|
|
HMTi
|
SUV39H1
|
Chaetocin
|
[31]
|
|
PAHi
|
BRD4
|
MZ-1
|
[37]
|
|
BRD7
|
LP99, VZ185
|
[36, 38]
|
|
BRD9
|
LP99, VZ185, BI-9564
|
[29, 36, 38]
|
|
PRC1i
|
RING1
|
PRT4165
|
[27]
|
|
PRC2i
|
EZH2
|
GSK343
|
[34]
|
|
DNMTi
|
DNMT1
|
Aurintricarboxylic acid
|
[24]
|
- Type of target, target name, drug name and reference are indicated. HDACi: histone deacetylase inhibitor, HDMi: histone demethylase inhibitor, HMTi: histone methyltransferase inhibitor, PAHi: inhibitor of proteins binding to acetylated histones, PRCi: polycomb-repressive complex inhibitor, DNMTi: DNA methyltransferase inhibitor
