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Table 2 Sensitivity and specificity of the ctDNA methylation test and CEA in patients with tumor load

From: Circulating tumor DNA methylation marker MYO1-G for diagnosis and monitoring of colorectal cancer

Biopsy finding ctDNA methylation test (n = 804)*
n Positive results (n) Negative results (n) Sensitivity % Specificity %
Stage I 7 6 1 85.7  
Stage II 43 32 11 74.4  
Stage III 125 104 21 83.2  
Stage IV 227 197 30 86.8  
Total 402 339 63 84.3  
Normal controls 402 22 380   94.5