From: Circulating tumor DNA methylation marker MYO1-G for diagnosis and monitoring of colorectal cancer
Biopsy finding | ctDNA methylation test (n = 804)* | ||||
---|---|---|---|---|---|
n | Positive results (n) | Negative results (n) | Sensitivity % | Specificity % | |
Stage I | 7 | 6 | 1 | 85.7 | Â |
Stage II | 43 | 32 | 11 | 74.4 | Â |
Stage III | 125 | 104 | 21 | 83.2 | Â |
Stage IV | 227 | 197 | 30 | 86.8 | Â |
Total | 402 | 339 | 63 | 84.3 | Â |
Normal controls | 402 | 22 | 380 | Â | 94.5 |