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Fig. 1 | Clinical Epigenetics

Fig. 1

From: DNA methylation signatures associated with cardiometabolic risk factors in children from India and The Gambia: results from the EMPHASIS study

Fig. 1

Epigenome-wide association analysis of systolic blood pressure in the Gambian cohort. A Manhattan plot of EWAS results with respect to systolic blood pressure (SBP) in the Gambian data. Red line indicates the Benjamini–Hochberg FDR threshold of 0.05. Significant dmCpGs (FDR < 0.05) are highlighted in red and labelled with the gene associated with them or the CpG name if intergenic. B–C Relationship between methylation beta value at B cg13455829 (MED22) and C cg22671726 (EGLN2) and SBP residual (mmHg) in 289 Gambian children. Shaded area around the regression line denotes the 95% confidence interval. EWAS, Epigenome-wide association study

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