Table 1 Univariate and multivariate of Cox proportional hazard modeling of factors associated with survival of CRC patients
Variable | Hazard ratio | (95% CI) | P value |
|---|---|---|---|
(1) Univariate analysis of overall survival | |||
 Age | 0.97 | 0.93–1.00 | 0.2 |
 Gender (female vs. male) | 0.86 | 0.36–2.00 | 0.7 |
 TNM stage | 2.26 | 1.23–4.17 | 0.009 |
 PMF of UNC5A | 1.51 | 0.35–6.12 | 0.6 |
 PMF of UNC5C | 5.83 | 1.43–23.85 | 0.014 |
 PMF of UNC5D | 6.10 | 1.48–25.04 | 0.012 |
 PMF of Sept9 | 5.58 | 1.21–25.63 | 0.026 |
(2) Multivariate analysis of overall survival | |||
 TNM stage1 | 3.39 | 1.65–6.95 | 0.001 |
 PMF of UNC5C1 | 15.06 | 3.12–72.65 | 0.001 |
 TNM stage2 | 2.61 | 1.37–4.98 | 0.004 |
 PMF of UNC5D2 | 10.02 | 2.13–47.08 | 0.003 |
 TNM stage3 | 2.54 | 1.26–5.11 | 0.009 |
 PMF of Sept93 | 5.95 | 1.30–27.24 | 0.022 |
(3) Univariate analysis of progress free survival | |||
 Age | 1.00 | 0.97–1.06 | 1.0 |
 Gender (female vs. male) | 0.94 | 0.46–1.92 | 0.9 |
 TNM stage | 1.73 | 1.07–2.77 | 0.023 |
 PMF of UNC5A | 1.81 | 0.62–5.43 | 0.3 |
 PMF of UNC5C | 3.44 | 1.12–10.56 | 0.03 |
 PMF of UNC5D | 4.77 | 1.48–15.34 | 0.009 |
 PMF of Sept9 | 2.05 | 0.73–5.81 | 0.2 |
(4) Multivariate analysis of progress free survival | |||
 TNM stage4 | 1.97 | 1.19–3.26 | 0.008 |
 PMF of UNC5C4 | 4.81 | 1.50–15.38 | 0.008 |
 TNM stage5 | 1.90 | 1.15–3.13 | 0.012 |
 PMF of UNC5D5 | 6.17 | 1.81–20.99 | 0.004 |