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Fig. 5 | Clinical Epigenetics

Fig. 5

From: Promoter methylation-mediated repression of UNC5 receptors and the associated clinical significance in human colorectal cancer

Fig. 5

The clinical significance of methylation alterations of UNC5 receptors in CRC. A scatterplots of the methylation levels of SEPT9, a well-known highly methylated gene in CRC tissues. B The correlation between the methylation levels of UNC5A, UNC5C, UNC5D and SEPT9 in CRC specimens. C ROC analysis was performed to evaluate the performances of methylation alterations of UNC5A, UNC5C, UNC5D and SEPT9 in discriminating adjacent non-cancerous tissues from CRC tissues. Kaplan–Meier analysis were performed for progression-free survival (D) and overall survival (E) in CRC patients with different methylation levels of UNC5A, UNC5C, UNC5D and SEPT9

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