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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Promoter methylation-mediated repression of UNC5 receptors and the associated clinical significance in human colorectal cancer

Fig. 4

Methylation-mediated repression of UNC5 receptors in clinical samples of CRC. A Pyrosequencing results of UNC5A, UNC5C and UNC5D in randomly selected paired CRC specimens. B The corresponding methylight results of UNC5A, UNC5C and UNC5D in the selected CRC specimens. C Comparison of results from pyrosequencing and methylight assay. D Scatterplots of the methylation levels of UNC5A, UNC5C and UNC5D detected by methylight in 59 paired CRC specimens. E Scatterplots of the relative expression levels of UNC5A, UNC5C and UNC5D detected by real-time PCR in 21 paired CRC specimens. F The correlation between the expression of and the promoter methylation levels of UNC5A, UNC5C and UNC5D in 21 paired CRC specimens

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