Fig. 2

Promoter methylation and expression of UNC5 receptors in TCGA dataset of CRC. A promoter methylation analysis of UNC5 receptors in TCGA dataset of CRC using Methylation Plotter. B scatter plots of the mean promoter methylation levels of UNC5 receptors in TCGA dataset of CRC. Each point represented the mean methylation levels (beta values) of promoter CpG sites in CRC (red) or paired normal tissues (blue). C Comparison of TPM expression of each receptor between normal and tumor tissues of CRC. D The association between expression and methylation of each receptor