Fig. 3
From: DNA methylation mediates the association between breastfeeding and early-life growth trajectories
Change in BMI mediated by DNA methylation from the combined effect of multiple CpG sites where DNA methylation is induced by different durations (3,4 and 5 months vs. no breastfeeding) of exclusive breastfeeding (EBF) in ALSPAC girls and boys and at different ages from birth to 17 years. The CpG sites in the final multi-mediator model were selected by forward selection (see “Methods” section). Each curve represents a smooth estimate function (loess estimate) of BMI changes over time and the confidence bands are the 95% confidence intervals of the smoothed curve