Table 1 Clinical characteristics of CPA patients with or without pregnancy
| Characteristics |
CPA without pregnancy (n = 12) |
CPA with pregnancy (n = 4) | P value |
|---|---|---|---|
| Age (years) | 30.08 ± 3.11 | 28.50 ± 2.33 | 0.783 |
| BMI (kg/m2) | 24.90 ± 1.14 | 27.68 ± 0.69 | 0.197 |
| SBP (mmHg) | 149.83 ± 5.01 | 152.50 ± 3.66 | 0.773 |
| DBP (mmHg) | 102.00 ± 2.87 | 97.00 ± 3.08 | 0.365 |
| Duration of disease (months) | 25.92 ± 5.81 | 4.25 ± 0.85 | 0.003 |
| K (mmol/L) | 3.63 ± 0.15 | 2.93 ± 0.41 | 0.057 |
| FSH (IU/L) | 5.14 ± 0.49 | 0.13 ± 0.02 | < 0.001 |
| LH (IU/L) | 4.00 ± 0.46 | 0.19 ± 0.03 | < 0.001 |
| E2 (pmol/L) | 296.48 ± 65.25 | 7446.43 ± 610.97 | 0.001 |
| PRL (nmol/L) | 86.42 ± 6.49 | 192.30 ± 48.13 | 0.002 |
| P (nmol/L) | 1.11 ± 0.50 | 161.70 ± 5.58 | < 0.001 |
| HCG (IU/L) | 0.27 ± 0.09 | 45,658.00 ± 9511.54 | < 0.001 |
| Cortisol (nmol/L) (8 am) | 593.06 ± 51.29 | 975.35 ± 140.51 | 0.006 |
| Cortisol (nmol/L) (4 pm) | 577.95 ± 44.19 | 984.74 ± 150.99 | < 0.001 |
| Cortisol (nmol/L) (12 pm) | 554.11 ± 60.96 | 935.13 ± 81.89 | 0.006 |
| ACTH (pmol/L) (8 am) | < 1.00 | < 1.00 | – |
| ACTH (pmol/L) (4 pm) | < 1.00 | < 1.00 | – |
| ACTH (pmol/L) (12 pm) | < 1.00 | < 1.00 | – |
| Tumor size (cm2) | 10.31 ± 1.01 | 10.69 ± 0.80 | 0.830 |
| Growth rate of tumor (m2/month) | 1.00 ± 0.33 | 2.86 ± 0.57 | 0.012 |