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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Alterations of DNA methylation were associated with the rapid growth of cortisol-producing adrenocortical adenoma during pregnancy

Fig. 3

DNA methylation and functional analysis of the overall region between the adjacent tissue and adenoma tissue of the non-pregnant patients with CPA. A Volcano graph illustrating the difference in DNA methylation across the entire chromatin region between the adjacent tissue and adenoma tissue of the non-pregnant patients with CPA. B The heatmap of DNA methylation differences in the overall region stratified by hyper- and hypo-DMPs that previously reported. C, D Enriched GO (Top 30) and KEGG pathways (Top 20) in hypo-DMPs associated with DNA hypomethylation genes in the adenoma tissue of the non-pregnant patients. E PPI and functional enrichment network of the overall region hypomethylated DMPs associated genes in the adenoma tissue of the non-pregnant patients using the STRING and Cytoscape software

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Clinical Epigenetics

ISSN: 1868-7083

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