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Table 2 Clinical data of PCa patients analyzed by IHC using TMA with regard to TET1 expression (n = 371 patients in total)

From: Tracing TET1 expression in prostate cancer: discovery of malignant cells with a distinct oncogenic signature

 

Count (%)

Age (y)

PSA (ng/mL)

Median

Range

Median

Range

Low risk

97 (26.2%)

64.6

48.5–78.3

5.74

0.2–38.4

Intermed. risk

45 (12.1%)

64.9

50.6–76.9

12.9

2.9–83.8

High risk

229 (61.7%)

65.5

46.7–77.4

9.9

0.3–113

T2a–c

165 (44.5%)

65.1

46.7–78.3

7.2

0.2–45.1

T3a-b

144 (38.8%)

65.9

54.1–77.4

8.7

0.3–74.8

T4

62 (16.7%)

63.2

50.6–76.5

15.8

2.8–113

GS ≤ 6

73 (19.7%)

64.3

48.5–77.1

5.6

0.2–83.8

GS7

69 (18.6%)

65.6

50.6–78.3

8.0

2.9–50

GS8

147 (39.6%)

66.1

46.7–77.4

10.5

0.3–113

GS ≥ 9

82 (22.1%)

64.6

51.1–77.1

8.8

0.3–65.5

  1. PCa prostate cancer, IHC immunohistochemical analysis, TMA tissue microarray, TET1 ten–eleven translocation family member 1, y years, PSA prostate-specific antigen, T tumor stage, GS Gleason score, Intermed. risk intermediate risk