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Fig. 7 | Clinical Epigenetics

Fig. 7

From: Tracing TET1 expression in prostate cancer: discovery of malignant cells with a distinct oncogenic signature

Fig. 7

Comparison of TET-coactivated genes in PCa and Tet1-bound genes in mouse trophoblast stem cells. TET1-coactivated genes in PCa (626) were analyzed in parallel to genes exhibiting Tet1-binding sites within the TSS1500-promoter (2691) with regard to gene ontology (GO) term enrichment (bottom left), and gene set enrichment (bottom right; MsigDB: Molecular Signatures Database). The results showed enrichment of nearly exactly the same GO terms (primarily associated with chromatin modification) and gene sets (primarily associated with mitotic division) in the two groups

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Clinical Epigenetics

ISSN: 1868-7083

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