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Table 2 Shared gene ontology annotations for enrichment analyses on CpG probes that exhibited a β values difference < − 0.1 before and after ionizing radiation of HepG2, MeWo-LC1, and U251 cell lines

From: Ionizing radiations induce shared epigenomic signatures unraveling adaptive mechanisms of cancerous cell lines with or without methionine dependency

GO biological process complete HepG2* MeWo-LC1* U251*
FE P-value FDR, P-value FE P-value FDR, P-value FE P-value FDR, P-value
Regulation of neuron projection development (GO:0010975) 2.03 4.69 × 10–6 1.35 × 10–3 2.42 1.05 × 10–5 1.84 × 10–2 2.43 6.78 × 10–5 3.25 × 10–2
Regulation of plasma membrane-bounded cell projection organization (GO:0120035) 1.97 2.76 × 10–7 1.25 × 10–4 2.14 1.58 × 10–5 2.28 × 10–2 2.25 2.07 × 10–5 1.72 × 10–2
Regulation of cell projection organization (GO:0031344) 1.92 6.05 × 10–7 2.33 × 10–4 2.09 3.50 × 10–5 4.25 × 10–2 2.19 4.32 × 10–5 2.53 × 10–2
Nervous system development (GO:0007399) 1.63 6.94 × 10–12 1.22 × 10–8 1.56 1.22 × 10–5 1.93 × 10–2 1.68 1.76 × 10–6 2.53 × 10–3
  1. FE: fold enrichment; DFR: false discovery rate
  2. *No significant GO annotation was found for the CpG probes that exhibited a β values difference < −0.1 before and after ionizing radiation for MeWo cell line