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Table 4 Overlapping cord blood differentially methylated regions for metals among infants overall (Sidak p < 0.05)

From: Prenatal metal exposure, cord blood DNA methylation and persistence in childhood: an epigenome-wide association study of 12 metals

Analysis

Chr

Start

End

Gene

Length

Number of probes

Hg

6

30,039,374

30,039,548

RNF39

175

12

Mg

 

30,039,175

30,039,548

RNF39

374

13

Mg

6

32,063,991

32,064,258

TNXB

268

12

Mn

 

32,063,726

32,064,161

TNXB

436

13

Cs

20

57,427,274

57,427,762

GNAS;GNASAS

489

16

Cu

 

57,427,426

57,427,942

GNAS;GNASAS

517

17

Mg

 

57,427,170

57,427,973

GNAS;GNASAS

804

24

  1. Differentially methylated regions (DMRs) identified using comb-p adjusted for infant sex, race/ethnicity, gestational age, nulliparous, maternal age at enrollment, pre-pregnancy BMI, education, smoking, household income, and estimated cord blood cell-type proportions
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Clinical Epigenetics

ISSN: 1868-7083

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