Table 5 DMPs with effect sizes ≥ 0.3 after stringent filtering
From: Epigenetic adaptations of the masticatory mucosa to periodontal inflammation
Probe ID | Chr:Position (hg19) | Distance to nearest significant DMP (bp) | Sup-porting DMPs (n) | Gene Symbol | Median TPM* | p (full analysis) | q (full analysis) | padj (paired analysis) | ∆β (full analyis) | Raw beta values (mean) | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Uninflamed (n = 48) | Inflamed (n = 48) | pGECs (n = 5) | Blood** (n = 69) | ||||||||||
cg14991316 | chr20:36,932,377 | 8 | 3 | BPI | 0 | 4.0 × 10–11 | 3.1 × 10–5 | 1.0 × 10–3 | − 0.34 | 0.67 | 0.12 | 0.92 | 0.06 |
cg09514933 | chr2:242,605,566 | 185 | 3 | ATG4B | 554 | 7.9 × 10–14 | 6.2 × 10–8 | 1.4 × 10–3 | − 0.33 | 0.89 | 0.76 | 0.94 | 0.96 |
cg10539002 | chr10:117,061,032 | 561 | 1 | ATRNL1 | 22 | 9.5 × 10–11 | 7.4 × 10–5 | 1.3 × 10–3 | − 0.31 | 0.53 | 0.28 | 0.42 | 0.67 |
cg11804639 | chr8:97,056,896 | 523 | 1 | GAPDHP30 | NA | 1.2 × 10–10 | 9.7 × 10–5 | 3.5 × 10–3 | − 0.31 | 0.77 | 0.37 | 0.66 | NA |
cg15528852 | chr7:41,137,006 | 40 | 1 | LINC01449 | NA | 1.9 × 10–8 | 1.5 × 10–2 | 5.0 × 10–4 | − 0.31 | 0.68 | 0.51 | 0.64 | 0.85 |
cg18450582 | chr7:95,546,539 | 31 | 1 | DYNC1I1 | 15 | 2.4 × 10–10 | 1.8 × 10–4 | 9.6 × 10–4 | − 0.30 | 0.80 | 0.64 | 0.82 | 0.94 |
cg27130240 | chr16:88,943,533 | 356 | 3 | CBFA2T3 | 72 | 9.3 × 10–9 | 7.2 × 10–3 | 7.5 × 10–2 | − 0.30 | 0.72 | 0.74 | 0.64 | 0.99 |