Table 2 Gene expression and DNA methylation differences between males and females for three genes across the cohorts used in the analysis
| Â | Gene expression effect size in males compared to females | Mean effect size of DMR showing largest effect size (% DNA methylation difference between males and females) | ||
|---|---|---|---|---|
GTEx (MASH posterior effect size) | FUSION (fold change) | Gene SMART (fold change) | ||
GGT7 | 0.81 | 1.6 | 3.5 | − 20.4 |
FOXO3 | − 0.04 | − 0.2 | 3.0 | − 1.9 |
ALDH1A1 | 0.33 | 0.4 | 2.8 | − 10 |