Skip to main content

Table 2 Gene expression and DNA methylation differences between males and females for three genes across the cohorts used in the analysis

From: Skeletal muscle methylome and transcriptome integration reveals profound sex differences related to muscle function and substrate metabolism

  Gene expression effect size in males compared to females Mean effect size of DMR showing largest effect size (% DNA methylation difference between males and females)
GTEx (MASH posterior effect size) FUSION (fold change) Gene SMART (fold change)
GGT7 0.81 1.6 3.5 − 20.4
FOXO3 − 0.04 − 0.2 3.0 − 1.9
ALDH1A1 0.33 0.4 2.8 − 10