Fig.1
From: H3K36 trimethylation-mediated biological functions in cancer
Protein structure and binding sites of H3K36me3-associated epigenetic regulators. a SETD2 is the sole histone methyltransferase of H3K36me3. See the text for the function of each domain. b The typical protein domain compositions of demethylase family KDM4. c Schematic diagram for several critical domains of readers which contribute to binding H3K36me3