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Fig. 6 | Clinical Epigenetics

Fig. 6

From: Prenatal and postnatal traffic pollution exposure, DNA methylation in Shank3 and MeCP2 promoter regions, H3K4me3 and H3K27me3 and sociability in rats’ offspring

Fig. 6

Three-chamber social test (n = 10 per group). Cumulative time spent in the chamber containing a novel rat (N1) and one without it was determined to assess sociability (A, C). In the social novelty phase (B, D), this ability was judged by cumulative time spent in the chambers holding a unfamiliar rat (N2) and the previous one (N1), respectively. L: green space H: crossroads. E: exposure from E0 to E20; P: exposure from PND1 to PND21. Student’s t-test conducted during all testing. *P < 0.05, **P < 0.01, ***P < 0.001.

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