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Fig. 6 | Clinical Epigenetics

Fig. 6

From: Epigenetic targeting of the ACE2 and NRP1 viral receptors limits SARS-CoV-2 infectivity

Fig. 6

VPA does not interfere with the synthesis of SARS-CoV-2 proteins. HK-2 and Huh-7 cells were infected with SARS-CoV-2 (MOI 0.5), and treated with VPA (4, 8, and 16 mM) 1 hpi. gRNA/sg mRNA expression levels (a) and protein levels (b) of protein N were analyzed at 6 and 16 hpi. GADPH (a) gene and β-actin (b) were used as endogenous controls for quantification of N gRNA/sg mRNA and protein levels. Data are presented as the mean ± SD of at least three independent experiments. Mock; mock-infected cells (b). * p < 0.05

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