Table 4 CpGs associated with prenatal risk are linked to genes that have been associated with traits in the GWASdb
From: Prenatal risk factors and neonatal DNA methylation in very preterm infants
Gene | Traits (N) | Selected traits |
|---|---|---|
BNIP3 | 8 | Self-reported educational attainment, intelligence, mathematical ability, household income, schizophrenia, cognitive function |
PRKAG2 | 38 | Self-reported educational attainment, mathematical ability, brain/neuroimaging measurement, gut microbiome measurement, white matter microstructure, cardiovascular disease, brain volume measurement, bipolar disorder, psychotic symptoms, cognitive function |
ZDHHC11 | 1 | Myopia age of onset |
LOC101929023 | – | – |
LINC00261 | 4 | Body mass index, fasting blood glucose measurement, birth weight |
IGSF5 | 4 | Systolic blood pressure, hypertension, short-term memory, health literacy |
KIF26B | 15 | Brain volume/neuroimaging measurement, response to SSRI, unipolar depression, diet measurement, brain measurement, schizophrenia |
COG4 | 3 | Body height, body weight, body mass index |
C15orf54 | 1 | Dihydroxy docosatrienoic acid measurement |
ZNF398 | 10 | Brain volume/neuroimaging measurement, white blood cell count |
ROPN1B | – | – |
CDCA4 | 1 | Telomere length |
CRYBB2P1 | 4 | Bipolar disorder |
TACC2 | 16 | Opioid dependence, metabolite measurement, body weight gain, schizophrenia, body height, reaction time measurement |
MASP1 | 3 | Type 2 diabetes |
MBIP | 6 | Self-reported educational attainment, hypertension |