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Table 2 Characteristics of patients with BCORMUT or BCORWT received decitabine therapy

From: Dynamics of epigenetic regulator gene BCOR mutation and response predictive value for hypomethylating agents in patients with myelodysplastic syndrome

Characteristics

BCORWT (n = 181)

BCORMUT (n = 14)

p value

Age, median (range), year

62 (17–85)

62 (23–80)

0.558

Gender, male:female, n (%)

120:61 (66:34)

7:7 (50:50)

0.250

WHO/FAB classification, n (%)

  

0.891

 RCMD

47 (26.0)

3 (21.4)

 

 RAEB-1

57 (31.5)

3 (21.4)

 

 RAEB-2

39 (21.5)

5 (35.7)

 

 RAEB-t

12 (6.6)

1 (7.1)

 

 CMML-1

17 (9.4)

1 (7.1)

 

 CMML-2

9 (5.0)

1 (7.1)

 

IPSS risk, n (%)

  

0.858

 Intermediate-1

84 (46.4)

7 (50.0)

 

 Intermediate-2

77 (42.5)

5 (35.7)

 

 High

20 (11.1)

2 (14.3)

 

Cytogenetic risk group, n (%)

   

 Good

108 (59.7)

12 (85.7)

0.072

 Intermediate

31 (17.1)

2 (14.3)

 

 Poor

42 (23.2)

0

 

Decitabine cycles, median (range), n

4 (1–11)

4 (2–7)

0.411