Table 1 Comparison of clinical parameters between BCORMUT and BCORWT patients
Characteristics | BCOR mutated (n = 43) | BCOR wild-type (n = 633) | p |
|---|---|---|---|
Age (mean) (year) | 55.8 | 55.9 | 0.970 |
Sex (M/F) (no) (ratio) | 24/19 (1.3) | 371/262 (1.4) | 0.719 |
Normal chromosomes (n) (%) | 31/43 (72.1) | 355/633 (56.1) | 0.040 |
RAEB (1 + 2) (n) (%) | 23/43 (53.5) | 174/633 (27.5) | 0.008 |
IPSS ≥ 1.5 (n) (%) | 15/43 (34.9) | 149/633 (23.5) | 0.093 |
AML transformation ratio (n) (%) | 11/43 (25.6) | 97/633 (15.3) | 0.076 |
Median overall survival (m) | 32 | 36 | 0.214 |
AML free survival (m) | 16 | 35 | 0.035 |