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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Dynamics of epigenetic regulator gene BCOR mutation and response predictive value for hypomethylating agents in patients with myelodysplastic syndrome

Fig. 4

RNA-sequencing analysis in patients with BCORMUT and BCORWT a Hierarchical clustering plot of the fold changes of gene expressions in three MDS patient with BCORMUT and three cases with BCORWT detected by RNA-sequencing (FC > 1.5, p values < 0.05). b KEGG pathway enrichment analysis c The top 10 enriched GO terms in biological process, cellular component, and molecular function. d HOX cluster genes including HOXA6, HOXB7and HOXB9 were significantly over-expressed in patients with BCORMUT

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