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Fig. 7 | Clinical Epigenetics

Fig. 7

From: DNA 5-hydroxymethylcytosine in pediatric central nervous system tumors may impact tumor classification and is a positive prognostic marker

Fig. 7

Venn diagram of shared CpGs in adult and pediatric tumor high 5hmC loci and methylation-based classification system’s most variable loci. The overlap of high 5hmC sites identified in pediatric tumors and adult glioblastomas with the most variable CpGs in the Capper data set with high 5hmC loci in pediatric and adult CNS tumors. There was considerably greater overlap between adult glioblastoma’s high 5hmC loci and the Capper data sets most variable CpGs (18%) than with the pediatric tumors’ high 5hmC CpGs (2%)

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Clinical Epigenetics

ISSN: 1868-7083

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