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Fig. 4 | Clinical Epigenetics

Fig. 4

From: DNA methylome profiling reveals epigenetic regulation of lipoprotein-associated phospholipase A2 in human vulnerable atherosclerotic plaque

Fig. 4

Integrated analysis of methylation and transcriptomic profiles of human atherosclerotic plaques. a Venn diagram depicting the number of genes hypomethylated in SYM compared with ASYM plaques (green), upregulated in advanced compared with early human carotid plaques (blue), and upregulated in macrophages from rupture compared with stable human coronary plaques (red). b GO biological process terms of genes enriched biological process. The size of the spots indicates the number of genes in the corresponding functional term. SYM, symptomatic; ASYM, asymptomatic; and GO, gene ontology

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