Skip to main content
Fig. 3 | Clinical Epigenetics

Fig. 3

From: Transcriptional epigenetic regulation of Fkbp1/Pax9 genes is associated with impaired sensitivity to platinum treatment in ovarian cancer

Fig. 3

Bisulfite sequencing of PAX9 and FKBP1B regulatory CGIs. Representation of ​​bisulfite-modified DNA fragment of both candidate genes from the sensitive and resistant tumor lines A2780 and OVCAR3, as well as DNA obtained from healthy ovarian tissue (OC) from patients undergoing sex change, DNA from human peripheral blood mononuclear cells (PBMCs) and from the tumor lines HeLa, BT747, LoVo and PC3. Samples were sequenced with sense primer for PAX9 and antisense for FKBP1B except in OVCAR3-S. Asterisks indicate methylated positions

Back to article page