Table 3 SNPs involved in meQTLs found in the GWAS catalog
GWAS | Normal | Adjacent | Tumor | |
|---|---|---|---|---|
Traits | 1722 | 48 (3%) | 19 (1%) | 15 (1%) |
SNPs | 48,881 | 64 (0.1%) | 26 (0%) | 15 (0%) |
Age at menopause | 84 | 1 (1%) | 1 (1%) | 0 (0%) |
Alzheimer's disease (late onset) | 55 | 1 (2%) | 1 (2%) | 1 (2%) |
Asthma | 206 | 2 (1%) | 0 (0%) | 1 (0%) |
Asthma or allergic disease (pleiotropy) | 36 | 1 (3%) | 0 (0%) | 0 (0%) |
Blood metabolite levels | 195 | 1 (1%) | 1 (1%) | 0 (0%) |
Blood protein levels | 2772 | 10 (0%) | 7 (0%) | 2 (0%) |
Blood urea nitrogen levels | 111 | 1 (1%) | 0 (0%) | 0 (0%) |
Childhood ear infection | 19 | 2 (11%) | 2 (11%) | 2 (11%) |
Chronic lymphocytic leukemia | 73 | 1 (1%) | 0 (0%) | 1 (1%) |
Circulating chemerin levels | 4 | 4 (100%) | 0 (0%) | 0 (0%) |
Colorectal cancer | 116 | 3 (3%) | 1 (1%) | 1 (1%) |
Colorectal cancer or advanced adenoma | 94 | 1 (1%) | 0 (0%) | 0 (0%) |
Drug-induced liver injury (amoxicillin-clavulanate) | 2 | 1 (50%) | 1 (50%) | 0 (0%) |
Educational attainment (MTAG) | 1320 | 1 (0%) | 0 (0%) | 0 (0%) |
Eosinophil percentage of granulocytes | 179 | 1 (1%) | 1 (1%) | 1 (1%) |
Hair color | 449 | 1 (0%) | 0 (0%) | 0 (0%) |
Heart rate response to exercise | 20 | 1 (5%) | 1 (5%) | 1 (5%) |
Heel bone mineral density | 2262 | 1 (0%) | 0 (0%) | 0 (0%) |
High density lipoprotein cholesterol levels | 306 | 2 (1%) | 0 (0%) | 0 (0%) |
Highest math class taken (MTAG) | 1084 | 1 (0%) | 0 (0%) | 0 (0%) |
Intraocular pressure | 512 | 2 (0%) | 0 (0%) | 0 (0%) |
Liver enzyme levels | 9 | 1 (11%) | 0 (0%) | 0 (0%) |
Liver enzyme levels (gamma-glutamyl transferase) | 26 | 2 (8%) | 2 (8%) | 1 (4%) |
Lumiracoxib-related liver injury | 1 | 1 (100%) | 0 (0%) | 0 (0%) |
Mean platelet volume | 323 | 1 (0%) | 0 (0%) | 0 (0%) |
Medication use (adrenergics, inhalants) | 55 | 1 (2%) | 0 (0%) | 0 (0%) |
Menopause (age at onset) | 63 | 1 (2%) | 1 (2%) | 0 (0%) |
Metabolite levels | 66 | 2 (3%) | 0 (0%) | 0 (0%) |
Metabolite levels (small molecules and protein measures) | 32 | 1 (3%) | 0 (0%) | 0 (0%) |
Multiple sclerosis | 158 | 1 (1%) | 0 (0%) | 0 (0%) |
Multiple sclerosis (OCB status) | 6 | 2 (33%) | 1 (17%) | 1 (17%) |
Oligoclonal band status in multiple sclerosis | 1 | 1 (100%) | 1 (100%) | 1 (100%) |
Plasma homocysteine levels (post-methionine load test) | 5 | 1 (20%) | 1 (20%) | 0 (0%) |
Platelet count | 323 | 1 (0%) | 0 (0%) | 0 (0%) |
Plateletcrit | 258 | 1 (0%) | 0 (0%) | 0 (0%) |
Pulse pressure | 747 | 1 (0%) | 0 (0%) | 0 (0%) |
Red cell distribution width | 821 | 1 (0%) | 0 (0%) | 0 (0%) |
S-phenylmercapturic acid levels in smokers | 1 | 1 (100%) | 0 (0%) | 0 (0%) |
Serum metabolite levels | 76 | 1 (1%) | 1 (1%) | 0 (0%) |
Systemic lupus erythematosus | 195 | 1 (1%) | 1 (1%) | 1 (1%) |
Systolic blood pressure | 1393 | 1 (0%) | 0 (0%) | 0 (0%) |
Triglyceride levels in current drinkers | 39 | 1 (3%) | 0 (0%) | 0 (0%) |
Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction | 55 | 1 (2%) | 0 (0%) | 0 (0%) |
Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction | 55 | 1 (2%) | 0 (0%) | 0 (0%) |
Type 1 diabetes | 87 | 1 (1%) | 0 (0%) | 1 (1%) |
Type 2 diabetes | 352 | 1 (0%) | 1 (0%) | 1 (0%) |
Urinary 1,3-butadiene metabolite levels in smokers | 2 | 2 (100%) | 1 (50%) | 1 (50%) |
White blood cell count | 854 | 2 (0%) | 1 (0%) | 0 (0%) |