Skip to main content

Table 1 Clinical parameters

From: Whole-genome methylation analysis of testicular germ cells from cryptozoospermic men points to recurrent and functionally relevant DNA methylation changes

Clinical parameters*

CTR1

CTR2

CTR3

CTR4

CZ1

CZ2

CZ3

CZ4

Diagnosis

Obstructive azoospermia

Cryptozoospermia

Age (Years)

31

33

55

32

39

41

29

23

Testicular volume (ml)

18

25

21

20

7

17

11

16

Total Sperm Count (≥ 39 × 106)

0

0

0

0

 < 0.1

 < 0.1

 < 0.1

 < 0.1

FSH (2–10 U/l)

2

3.3

8.2

4.8

8.5

6.5

5.8

3

LH (1–7 U/l)

2.1

2

7.1

3.5

2.5

5.4

6.1

2.6

Total Testosterone (> 12 nmol/l)

16.5

25.1

66

19.9

18.7

13.4

12.7

17.5

Karyotype

46,XY

46,XY

NA

46,XY

46,XY

46,XY

46,XY

NA

Sperm in micro TESE

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Bergmann-Kliesch score

9

8

8

7

1

0.4

4

3

  1. FSH follicle stimulating hormone, LH luteinizing hormone, TESE testicular sperm extraction. Normal levels of sperm counts and hormones are shown in parentheses