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Fig. 5 | Clinical Epigenetics

Fig. 5

From: DNA methylation patterns at and beyond the histological margin of early-stage invasive lung adenocarcinoma radiologically manifested as pure ground-glass opacity

Fig. 5

Variations of DNA methylation levels for the MHB, DMC, and DMR markers from tumor core (TC) to peripheral normal tissues (PN). Each type of methylation markers was divided into four groups: high-score S markers, low-score S markers, high-score G markers, and low-score G markers. Five representative markers were selected from each group to show their variation patterns from TC to PN. S markers showed less change in the methylation score between TC and TE than that between TE and para-tumor tissues (P5–PN) in individual samples. G markers demonstrated similar to or even greater difference between the methylation scores of TC and TE than that between P5 and TE

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Clinical Epigenetics

ISSN: 1868-7083

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