| Control group (N = 58) | Depressed group (baseline, N = 80) | Significance |
---|---|---|---|
Age (year, mean ± SD) | 45.5 ± 12.0 | 45.4 ± 12.1 | t = 0.08 |
p = 0.93 | |||
Gender (N, female/male) | 31/27 | 47/33 | X2 = 0.38 |
p = 0.53 | |||
Educational level (low/high)a | 13/45 | 48/32 | X2 = 19.3 |
p < 0.001** | |||
Antidepressant use (%) | |||
None | 96.6 | 4 | - |
SSRI | 1.7 | 41 | Â |
SNRI | 0 | 34 | Â |
Other (TCA, mirtazapine, bupropion) | 1.7 | 21 | Â |
Early life stress event (% yes)b | 10.3 | 38.0 | X2 = 13.18, p < 0.001** |
Depression severity (HDRS) | 0.6 ± 1.3 | 16.9 ± 5.0 | t = 27.54, p < 0.001** |
Anhedonia (SHAPS) | 19.2 ± 4.1 | 35.7 ± 7.6 | t = 16.58, p < 0.001** |
Cognitive performance (percentile ± SD) | |||
SCWT | 65.3 ± 25.3 | 29.6 ± 2.5 | t = 8.28, p < 0.001** |
TMT-A | 67.8 ± 22.6 | 35.2 ± 23.0 | t = 8.26, p < 0.001** |
TMT-B | 65.2 ± 26.6 | 38.3 ± 26.4 | t = 5.86, p < 0.001** |
DS-F | 34.3 ± 25.5 | 29.7 ± 27.8 | t = 0.99, p = 0.32 |
DS-B | 45.9 ± 25.9 | 42.0 ± 25.5 | t = 0.87, p = 0.39 |