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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Genome wide DNA methylation analysis of alveolar capillary dysplasia lung tissue reveals aberrant methylation of genes involved in development including the FOXF1 locus

Fig. 4

Hypermethylation of the first exon of FOXF1 in an ACD/MPV patient without a genomic FOXF1 variant a Hypermethylated region encompassing the first exon of FOXF1 in ACD-none2, demonstrated in IGV viewer. Methylation patterns of ACD-none (red) and control samples (grey) are shown. b DNA methylation patterns of ACD-none lung tissues (light red), bowel tissue of ACD-none1 (light blue) and lymph tissue of ACD-none1 (dark blue) depicted with IGV viewer. Both lymph tissue of ACD-none1 and lung tissue of ACD-none2 demonstrate a highly methylated region covering exon 1

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