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Fig. 6 | Clinical Epigenetics

Fig. 6

From: Methylation status of nc886 epiallele reflects periconceptional conditions and is associated with glucose metabolism through nc886 RNAs

Fig. 6

nc886 epiallele methylation and metabolic traits. Associations between nc886 epiallele methylation status and yearly estimates (from ages 6–34) and measurements of a insulin, b glucose, c HDL cholesterol, d non-HDL cholesterol, e adiposity, and f liver enzymes. For adiposity, only yearly estimates from the YFS are available, while only biochemical measurements are available for liver enzymes. Values are expressed as standard deviation (SD) increments in metabolite measures and as 95% confidence intervals (95% CI) comparing individuals with a non-methylated nc886 epiallele to those with a hemi-methylated epiallele. Intermediately methylated individuals were excluded from the analysis due to low numbers. Nominal p value < 0.05 is indicated with red

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