DNA methylation under the major depression pathway predicts pediatric quality of life four-month post-pediatric mild traumatic brain injury

Table 4 Annotations of highlighted CpG sites (|z|> 2) of methylation ICs 1–5

IC	CpG sites	Chr	BP Pos	Z value	Relation to Island	RefGene name (UCSC)
IC 1	cg19097407	chr9	36154750	14.42	OpenSea	GLIPR2
IC 2	cg19519355	chr8	26697488	12.53	OpenSea	ADRA1A
	cg10492858	chr21	35884679	2.43	OpenSea	KCNE1
	cg06279296	chr10	601816	− 2.48	OpenSea	DIP2C
	cg21163960	chr11	35441777	− 2.12	Island	SLC1A2
	cg22186155	chr8	72765158	− 2.02	OpenSea	MSC-AS1
IC 3	cg08549495	chr16	8823986	12.55	OpenSea	ABAT
IC 3	cg00549601	chr12	52208872	4.42	Island
IC 4	cg03944460	chr4	3765186	12.82	N_Shore
	cg27297376	chr7	98627840	2.70	OpenSea	SMURF1
	cg06279296	chr10	601816	− 2.64	OpenSea	DIP2C
IC 5	cg04306507	chr14	55594613	12.62	N_Shore	LGALS3
IC 5	cg09422301	chr6	24494043	− 3.37	N_Shore	ALDH5A1

‘Chr’ and ‘BP Pos’ represent chromosome number and base pair position, respectively. ‘RefGene Name (UCSC)’ denotes reference gene name from University of California, Santa Cruz (UCSC) genome browser

ISSN: 1868-7083