Fig. 5
From: SETD2-mediated epigenetic regulation of noncanonical Wnt5A during osteoclastogenesis
SETD2 facilitated the expression of NF-κβ thus H3K9Ac and H4K8Ac enrichment. a RT-PCR analysis of NF-κβ expression in osteoclast differentiated and SETD2 knocked down and overexpressed samples. b ChIP-qRT-PCR analysis of H3K9Ac and H4K8Ac enrichment on the Wnt5a gene in osteoclast differentiated and C. SETD2 knocked down and overexpressed cells. ChIP with IgG from rabbit served as a negative control for all ChIP analyses